Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SGPL1 | O95470 | 6/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621981 | 0.84 | TACR1 (0.48) | MEN1KMT2ATACR1LMNAKDM4E | |
| SCHEMBL8621274 | 0.83 | MEN1 (0.52) | MEN1KMT2ATACR1LMNAKDM4E | |
| SCHEMBL7713389 | 0.83 | TACR1 (0.48) | MEN1KMT2ATACR1LMNAKDM4E | |
| SCHEMBL6557014 | 0.82 | MEN1 (0.73) | MEN1KMT2ATACR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8620824 | 0.81 | MEN1 (0.71) | MEN1KMT2ATACR1ALDH1A1ATM | |
| SCHEMBL8621287 | 0.80 | SGPL1 (0.52) | MEN1KMT2AKDM4EALDH1A1SGPL1 | |
| SCHEMBL15829272 | 0.74 | SLC6A4 (0.48) | MEN1KMT2ATACR1 | |
| SCHEMBL6555107 | 0.74 | MEN1 (0.68) | MEN1KMT2AKDM4EALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL8615245 | 0.73 | MEN1 (0.66) | MEN1KMT2AKDM4EALDH1A1ATM | |
| SCHEMBL11169196 | 0.72 | TACR1 (0.46) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613458-B1 | ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS | PFIZER (US) | 1998-01-07 | — | — | EP | disclosed |