SCHEMBL8626718

SCHEMBL8626718

NCCCN(C=CN(CCCN)CCCN)CCCN

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.38
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA3 P07451 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
DNM1 Q05193 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
BLM P54132 1/20 0.35
CHRM2 P08172 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294143 1.00 NFKB1 (0.38) NFKB1CA12CA1CA2CA3
SCHEMBL5238398 0.83 NFKB1 (0.30) NFKB1
SCHEMBL4693105 0.75 NFKB1 (0.33) NFKB1CA12CA1CA2CA3
SCHEMBL19253566 0.75 NFKB1 (0.33) NFKB1CA12CA1CA2CA3
SCHEMBL22705023 0.69 NFKB1 (0.40) NFKB1CA12CA1CA2CA3
SCHEMBL62173 0.67 NFKB1 (0.46) NFKB1CA12CA1CA2CA3
SCHEMBL23716689 0.65
SCHEMBL20391865 0.65 CHRM2 (0.46) NFKB1CA12CA1CA2CA3
SCHEMBL13913105 0.65 LCK (0.48) NFKB1CA12CA1CA2CA3
SCHEMBL636385 0.65 CHRM2 (0.45) NFKB1CA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750788-A Preparation of amines from compounds having at least 3 cyano groups BASF AKTIENGESELLSCHAFT (DE) 1998-05-12 US disclosed