SCHEMBL19253566

SCHEMBL19253566

C=CN(CCCN)CCCN

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CHRM2 P08172 1/20 0.32
CA12 O43570 3/20 0.32
CA2 P00918 3/20 0.32
CA4 P22748 3/20 0.32
CA6 P23280 3/20 0.32
CA5A P35218 3/20 0.32
CA7 P43166 3/20 0.32
CA9 Q16790 3/20 0.32
CA14 Q9ULX7 3/20 0.32
CA5B Q9Y2D0 3/20 0.32
CA1 P00915 2/20 0.32
CA3 P07451 2/20 0.32
DNM1 Q05193 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
BLM P54132 1/20 0.32
CASP2 P42575 2/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28281762 0.81
SCHEMBL22338145 0.78 DNM1 (0.35) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL20380911 0.77
SCHEMBL24423962 0.76
SCHEMBL8626718 0.75 NFKB1 (0.38) NFKB1CHRM2CA12CA2CA4
SCHEMBL6294143 0.75 NFKB1 (0.38) NFKB1CHRM2CA12CA2CA4
SCHEMBL12977946 0.72
SCHEMBL4693105 0.71 NFKB1 (0.33) NFKB1TDP1CHRM2CA12CA2
SCHEMBL14910454 0.69
Hydrochloric Acid SCHEMBL22575367 0.69 TSHR (0.39) CA12CA9CA1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3420016-B1 BENZYLATED MANNICH BASE CURING AGENTS, COMPOSITIONS, AND METHODS EVONIK OPERATIONS GMBH (DE) 2025-01-15 EP disclosed
US-10669370-B2 Benzylated mannich base curing agents, compositions, and methods EVONIK OPERATIONS GMBH (DE) 2020-06-02 US disclosed
CN-105102602-B Preparaton, its as or for product dish washing detersive purposes and its preparation 巴斯夫欧洲公司 2018-05-25 CN disclosed
US-20170240691-A1 BENZYLATED MANNICH BASE CURING AGENTS, COMPOSITIONS, AND METHODS EVONIK OPERATIONS GMBH (DE) 2017-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10669370-B2 Benzylated mannich base curing agents, compositions, and methods H1-0, SRM, H1-2 NFKB1 1305/4885TDP1 1658/4885CHRM2 1159/4885
US-20170240691-A1 BENZYLATED MANNICH BASE CURING AGENTS, COMPOSITIONS, AND METHODS H1-0, SRM, H1-2 NFKB1 1305/4885TDP1 1658/4885CHRM2 1159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.