Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278540 | 0.98 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5907164 | 0.98 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL9615934 | 0.84 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL1405818 | 0.84 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL1405817 | 0.84 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL4003166 | 0.83 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL1387512 | 0.83 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL27730076 | 0.83 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8057318 | 0.83 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL27807523 | 0.83 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |