Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.44 |
| ▸ | GJA1 | P17302 | 2/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 8/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625289 | 0.85 | GJB2 (0.39) | GJB2GJA1SSTR5TACR2SSTR1 | |
| SCHEMBL7997395 | 0.81 | LTA4H (0.39) | GJB2GJA1SLC5A2SLC5A1SSTR5 | |
| SCHEMBL8006235 | 0.80 | SLC5A1 (0.42) | GJB2GJA1SLC5A2SLC5A1NPC1 | |
| SCHEMBL8008165 | 0.80 | SLC5A1 (0.42) | GJB2GJA1SLC5A2SLC5A1NPC1 | |
| SCHEMBL8006236 | 0.80 | SLC5A1 (0.42) | GJB2GJA1SLC5A2SLC5A1NPC1 | |
| SCHEMBL8907490 | 0.80 | GJB2 (0.43) | GJB2GJA1SSTR5TACR2SSTR1 | |
| SCHEMBL8630332 | 0.80 | GJB2 (0.43) | GJB2GJA1SSTR5TACR2SSTR1 | |
| SCHEMBL28624520 | 0.80 | TACR2 (0.44) | GJB2SSTR5TACR2SSTR1SSTR2 | |
| SCHEMBL5689675 | 0.78 | SSTR5 (0.41) | GJB2GJA1SLC5A2SLC5A1SSTR5 | |
| SCHEMBL8907486 | 0.77 | GJB2 (0.47) | GJB2GJA1SLC5A2SLC5A1SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747463-A | SELECTIN ANTAGONISTS; ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| US-5663151-A | ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0671407-A2 | Sulfated alpha-glycolipid derivatives as cell adhesion inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |