Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ABL2 | P42684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626937 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2FBP1ABL1EGFRABL2 | |
| SCHEMBL8626310 | 0.82 | FBP1 (0.66) | SMN1; SMN2FBP1ABL1EGFRABL2 | |
| SCHEMBL8626306 | 0.82 | FBP1 (0.66) | SMN1; SMN2FBP1ABL1EGFRABL2 | |
| SCHEMBL11846459 | 0.81 | FBP1 (0.59) | SMN1; SMN2FBP1ABL1EGFRABL2 | |
| SCHEMBL11846466 | 0.81 | FBP1 (0.59) | SMN1; SMN2FBP1ABL1EGFRABL2 | |
| SCHEMBL14867131 | 0.79 | MGLL (0.56) | SMN1; SMN2FBP1ALDH1A1RAB9AMAPT | |
| SCHEMBL2748046 | 0.76 | FBP1 (0.66) | SMN1; SMN2FBP1ABL1EGFRABL2 | |
| SCHEMBL2748049 | 0.76 | FBP1 (0.66) | SMN1; SMN2FBP1ABL1EGFRABL2 | |
| SCHEMBL14230254 | 0.76 | FBP1 (0.66) | SMN1; SMN2FBP1ABL1EGFRABL2 | |
| SCHEMBL2748047 | 0.76 | FBP1 (0.66) | SMN1; SMN2FBP1ABL1EGFRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672646-B1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5639895-A | Process for producing β-nitroenamine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| US-5597940-A | REACTING NITROOLEFIN WITH HYDROXYLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0672646-A1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-20 | — | — | EP | disclosed |