Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20259387 | 0.94 | KDM4E (0.45) | GGT1FOLH1KDM4EMAPTTHRB | |
| SCHEMBL145047 | 0.93 | GGT1 (0.44) | GGT1FOLH1KDM4EMAPTTHRB | |
| SCHEMBL5507865 | 0.91 | GGT1 (0.43) | GGT1FOLH1KDM4EMAPTTHRB | |
| SCHEMBL20836757 | 0.89 | GGT1 (0.42) | GGT1FOLH1KDM4EMAPTTHRB | |
| SCHEMBL313184 | 0.89 | GGT1 (0.42) | GGT1FOLH1KDM4EMAPTTHRB | |
| SCHEMBL5867413 | 0.87 | GGT1 (0.41) | GGT1FOLH1KDM4EMAPTTHRB | |
| SCHEMBL27624627 | 0.87 | FOLH1 (0.48) | GGT1FOLH1ENPEPANPEPRIMKLA | |
| SCHEMBL474687 | 0.87 | GGT1 (0.41) | GGT1FOLH1KDM4EMAPTTHRB | |
| SCHEMBL474688 | 0.87 | GGT1 (0.41) | GGT1FOLH1KDM4EMAPTTHRB | |
| SCHEMBL3386652 | 0.84 | NOD1 (0.49) | GGT1KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444130-B1 | TECHNETIUM-99m COMPLEX FOR EXAMINING THE RENAL FUNCTION | MALLINCKRODT INC (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1990005733-A1 | TECHNETIUM-99m COMPLEX FOR EXAMINING THE RENAL FUNCTION | MALLINCKRODT, INC. (US) | 1990-05-31 | — | — | WO | disclosed |