Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593677 | 0.91 | ALDH1A1 (0.36) | ALDH1A1LMNAMEN1KMT2AOPRK1 | |
| SCHEMBL8480927 | 0.86 | NPSR1 (0.41) | ALDH1A1LMNAMEN1KMT2AOPRK1 | |
| SCHEMBL8479606 | 0.84 | SCN1A (0.37) | MEN1KMT2A | |
| SCHEMBL8503790 | 0.82 | SCN1A (0.32) | NPSR1GAA | |
| SCHEMBL8666693 | 0.82 | SCN1A (0.35) | — | |
| SCHEMBL8487923 | 0.79 | SCN1A (0.38) | MEN1KMT2A | |
| SCHEMBL8503698 | 0.77 | SCN1A (0.33) | L3MBTL1NPSR1GAA | |
| SCHEMBL8485533 | 0.77 | NPSR1 (0.42) | MEN1KMT2ANPSR1DRD2DRD3 | |
| SCHEMBL8664246 | 0.77 | SCN1A (0.35) | — | |
| SCHEMBL8479245 | 0.76 | SCN1A (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886637-A1 | INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-30 | — | — | EP | claimed |
| EP-0886637-A4 | — | — | 1998-12-30 | — | — | EP | claimed |