Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593677 | 0.89 | ALDH1A1 (0.36) | NPSR1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8627055 | 0.86 | ALDH1A1 (0.34) | NPSR1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8675063 | 0.86 | L3MBTL1 (0.42) | NPSR1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8485120 | 0.85 | TSHR (0.36) | NPSR1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8480408 | 0.85 | TMEM97 (0.38) | NPSR1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8503791 | 0.82 | TSHR (0.37) | NPSR1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8714742 | 0.82 | NPSR1 (0.39) | NPSR1DRD2HTR1AHTR2AALDH1A1 | |
| SCHEMBL8668070 | 0.81 | MEN1 (0.35) | NPSR1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8502237 | 0.81 | NPSR1 (0.38) | NPSR1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8669685 | 0.80 | NPSR1 (0.42) | NPSR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |