Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 18/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622356 | 1.00 | HDAC3 (0.65) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL8388600 | 1.00 | HDAC3 (0.65) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL8391919 | 1.00 | HDAC3 (0.65) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL8390586 | 0.91 | HDAC3 (0.77) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL8621081 | 0.87 | ALDH1A1 (0.60) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL8391654 | 0.87 | ALDH1A1 (0.60) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL8623286 | 0.87 | ALDH1A1 (0.60) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL8389301 | 0.87 | ALDH1A1 (0.60) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL7198042 | 0.83 | ALDH1A1 (0.56) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL8627027 | 0.81 | NAAA (0.54) | HDAC3HDAC1HDAC2HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648612-B1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5498772-A | SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER | MITSUBISHI PAPER MILLS LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0648612-A1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |