Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 8/20 | 0.38 |
| ▸ | HTR2B | P41595 | 8/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526575 | 0.79 | KDM1A (0.57) | KDM1AHTR2CHTR2BHTR2A | |
| SCHEMBL7526567 | 0.79 | KDM1A (0.57) | KDM1AHTR2CHTR2BHTR2A | |
| SCHEMBL8630599 | 0.78 | LARS1 (0.40) | KDM1AHTR2CHTR2BHTR2AALDH1A1 | |
| SCHEMBL6901277 | 0.74 | FFAR1 (0.42) | KDM1AHTR2CHTR2BHTR2A | |
| SCHEMBL6903831 | 0.74 | FFAR1 (0.42) | KDM1AHTR2CHTR2BHTR2A | |
| SCHEMBL6901272 | 0.74 | FFAR1 (0.42) | KDM1AHTR2CHTR2BHTR2A | |
| SCHEMBL12360653 | 0.72 | L3MBTL1 (0.38) | KDM1AFGFR2L3MBTL1ATMHPGD | |
| SCHEMBL6904145 | 0.72 | KDM1A (0.38) | KDM1AHTR2CHTR2BHTR2AHCRTR1 | |
| SCHEMBL6907311 | 0.69 | TSHR (0.40) | KDM1AHTR2CHTR2BFGFR2L3MBTL1 | |
| SCHEMBL7661595 | 0.69 | KDM1A (0.46) | KDM1AHTR2CHTR2BHTR2AFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849769-A | N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection | MEDIVIR AB (SE) | 1998-12-15 | — | — | US | disclosed |