Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 9/20 | 0.38 |
| ▸ | HTR2A | P28223 | 8/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906205 | 0.79 | KDM1A (0.54) | LARS1HTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL8627563 | 0.78 | KDM1A (0.39) | HTR2CHTR2AHTR2BKDM1ALMNA | |
| SCHEMBL6907447 | 0.74 | FFAR4 (0.41) | LARS1HTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL17527769 | 0.73 | L3MBTL1 (0.48) | KDM1AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12360652 | 0.72 | TP53 (0.36) | LARS1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6904152 | 0.72 | CA12 (0.41) | LARS1HTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL4412687 | 0.71 | ALDH1A1 (0.41) | LARS1HTR2CHTR2AKDM1AMAPT | |
| SCHEMBL4406805 | 0.71 | TRPV4 (0.37) | LARS1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL19890544 | 0.69 | L3MBTL1 (0.41) | LARS1HTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL4403785 | 0.69 | ALDH1A1 (0.39) | LARS1MAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849769-A | N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection | MEDIVIR AB (SE) | 1998-12-15 | — | — | US | disclosed |