SCHEMBL8627739

SCHEMBL8627739

O=P(Oc1ccccc1)(OC1COO1)OC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.36
SRC P12931 1/20 0.31
FAAH O00519 1/20 0.31
EPHX2 P34913 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
GPR84 Q9NQS5 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26979022 0.88 NPSR1 (0.34) NPSR1KMT2A
SCHEMBL6860645 0.84 NPSR1 (0.46) NPSR1SRCFAAHEPHX2TDP1
SCHEMBL6859520 0.84 NPSR1 (0.46) NPSR1SRCFAAHEPHX2TDP1
SCHEMBL702317 0.79 NPSR1 (0.45) NPSR1SRCFAAHEPHX2TDP1
SCHEMBL702315 0.76 NPSR1 (0.42) NPSR1SRCFAAHEPHX2TDP1
SCHEMBL8627735 0.74 SRC (0.41) NPSR1SRCFAAHEPHX2TDP1
SCHEMBL27495160 0.73 SRC (0.46) NPSR1SRCFAAHEPHX2TDP1
SCHEMBL4922666 0.71 NPSR1 (0.44) NPSR1
SCHEMBL8653632 0.71 SRC (0.47) SRCTDP1L3MBTL1GPR84
SCHEMBL15503836 0.69 NPSR1 (0.44) NPSR1SRCFAAHEPHX2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689655-A1 DETECTION OF AUTOANTIBODIES AGAINST NR1 Arialys Therapeutics, Inc. (US) 2026-02-11 EP disclosed
WO-2024206667-A1 DETECTION OF AUTOANTIBODIES AGAINST NR1 Arialys Therapeutics, Inc. (US) 2024-10-03 WO disclosed
EP-0662154-B1 Conjugate for the detection and/or assay of a biological compound WALLONE REGION (BE) 1998-06-10 EP disclosed
WO-1996027785-A1 ARTICLE AND METHOD FOR CONDUCTING CHEMILUMINESCENT REACTION ABBOTT LABORATORIES (US) 1996-09-12 WO disclosed
EP-0662154-A1 Conjugate for the detection and/or assay of a biological compound LAMBDATECH S.A. (BE) 1995-07-12 EP disclosed
WO-1994006933-A1 CONJUGATE FOR THE DETECTION AND/OR ASSAY OF A BIOLOGICAL COMPOUND LAMBDATECH S.A. (BE) 1994-03-31 WO disclosed