SCHEMBL702317

SCHEMBL702317

COP(=O)(Oc1ccccc1)OC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.45
PKM P14618 1/20 0.37
HTT P42858 1/20 0.37
GPR84 Q9NQS5 1/20 0.37
FAAH O00519 3/20 0.36
CNR2 P34972 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SRC P12931 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 1/20 0.35
LMNA P02545 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6860645 0.91 NPSR1 (0.46) NPSR1GPR84FAAHCNR2KMT2A
SCHEMBL6859520 0.91 NPSR1 (0.46) NPSR1GPR84FAAHCNR2KMT2A
SCHEMBL702315 0.89 NPSR1 (0.42) NPSR1PKMHTTGPR84FAAH
SCHEMBL27495160 0.79 SRC (0.46) NPSR1FAAHCNR2KMT2ASRC
SCHEMBL8627739 0.79 NPSR1 (0.36) NPSR1GPR84FAAHKMT2ASRC
SCHEMBL15503836 0.78 NPSR1 (0.44) NPSR1HTTGPR84FAAHCNR2
SCHEMBL132822 0.75 SRC (0.54) PKMHTTMEN1KMT2ASRC
SCHEMBL1725920 0.75 SRC (0.54) PKMHTTMEN1KMT2ASRC
SCHEMBL8627735 0.74 SRC (0.41) NPSR1FAAHCNR2KMT2ASRC
SCHEMBL6860350 0.73 FAAH (0.33) NPSR1HTTFAAHCNR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124026-B2 Lateral flow diagnostic devices with instrument controlled fluidics EPOCAL INC. (CA) 2012-02-28 US disclosed
US-20100202926-A1 LATERAL FLOW DIAGNOSTIC DEVICES WITH INSTRUMENT CONTROLLED FLUIDICS EPOCAL INC. (CA) 2010-08-12 US disclosed
US-7722817-B2 Lateral flow diagnostic devices with instrument controlled fluidics EPOCAL INC. (CA) 2010-05-25 US disclosed
US-20050047972-A1 Instrument controlled integrated, one step analyte detection and testing; consistency, sensitivity; simplicity, low cost, speed SIEMENS HEALTHCARE DIAGNOSTICS INC. 2005-03-03 US disclosed