SCHEMBL8627735

SCHEMBL8627735

C1COO1.O=P(O)(Oc1ccccc1)OC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.41
NPSR1 Q6W5P4 1/20 0.39
POLB P06746 1/20 0.37
FAAH O00519 3/20 0.36
EPHX2 P34913 2/20 0.35
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
P2RX7 Q99572 1/20 0.34
CNR2 P34972 2/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27495160 0.94 SRC (0.46) SRCNPSR1POLBFAAHEPHX2
SCHEMBL6859520 0.79 NPSR1 (0.46) SRCNPSR1FAAHEPHX2KMT2A
SCHEMBL6860645 0.79 NPSR1 (0.46) SRCNPSR1FAAHEPHX2KMT2A
Phenyl Dihydrogen Phosphate SCHEMBL5051597 0.75 SRC (0.58) SRCNPSR1FAAHEPHX2KMT2A
SCHEMBL702316 0.75 CNR2 (0.48) NPSR1FAAHEPHX2KMT2AP2RX7
SCHEMBL702317 0.74 NPSR1 (0.45) SRCNPSR1FAAHEPHX2ALDH1A1
SCHEMBL8627739 0.74 NPSR1 (0.36) SRCNPSR1FAAHEPHX2KMT2A
SCHEMBL4922662 0.73 NPSR1 (0.53) NPSR1KMT2A
SCHEMBL15503836 0.73 NPSR1 (0.44) SRCNPSR1FAAHEPHX2ALDH1A1
SCHEMBL17169179 0.73 NPSR1 (0.61) NPSR1EPHX2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689655-A1 DETECTION OF AUTOANTIBODIES AGAINST NR1 Arialys Therapeutics, Inc. (US) 2026-02-11 EP disclosed
WO-2024206667-A1 DETECTION OF AUTOANTIBODIES AGAINST NR1 Arialys Therapeutics, Inc. (US) 2024-10-03 WO disclosed
EP-0662154-B1 Conjugate for the detection and/or assay of a biological compound WALLONE REGION (BE) 1998-06-10 EP disclosed
EP-0662154-A1 Conjugate for the detection and/or assay of a biological compound LAMBDATECH S.A. (BE) 1995-07-12 EP disclosed
WO-1994006933-A1 CONJUGATE FOR THE DETECTION AND/OR ASSAY OF A BIOLOGICAL COMPOUND LAMBDATECH S.A. (BE) 1994-03-31 WO disclosed