Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632319 | 0.89 | NPC1 (0.46) | NPC1ALPLAKR1B1MAPTALDH1A1 | |
| SCHEMBL2104226 | 0.83 | TRPV1 (0.47) | ALPLMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL56146 | 0.81 | ALDH1A1 (0.51) | NPC1ALPLAKR1B1MAPTALDH1A1 | |
| SCHEMBL8627768 | 0.80 | NPC1 (0.50) | NPC1MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8629003 | 0.79 | NPC1 (0.49) | NPC1MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3715441 | 0.77 | ALPL (0.48) | NPC1ALPLAKR1B1MAPTALDH1A1 | |
| SCHEMBL8800996 | 0.77 | ALPL (0.45) | ALPLAKR1B1MAPTALDH1A1KDM4E | |
| SCHEMBL15212007 | 0.76 | ALPL (0.43) | NPC1ALPLAKR1B1MAPTALDH1A1 | |
| SCHEMBL13007730 | 0.76 | ALPL (0.47) | NPC1ALPLAKR1B1MAPTALDH1A1 | |
| SCHEMBL8630641 | 0.75 | MAPT (0.64) | NPC1MAPTALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824652-A | IMMUNOSTIMULANTS, ANTITUMOR AGENTS | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TECHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1998-10-20 | — | — | US | disclosed |
| EP-0695308-B1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIV LJUBLJANI (SI) | 1998-07-01 | — | — | EP | disclosed |
| EP-0695308-A1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024152-A1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1994-10-27 | — | — | WO | disclosed |