Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8627775

N.N.O=C1C=CC=CC1=O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
ALDH1A1 P00352 1/20 0.36
BCHE P06276 1/20 0.36
POLB P06746 1/20 0.36
ACHE P22303 1/20 0.36
APEX1 P27695 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
MDM2 Q00987 1/20 0.36
DHODH Q02127 1/20 0.36
HSD17B10 Q99714 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
IDO1 P14902 1/20 0.32
CDC25B P30305 1/20 0.32
AKT1 P31749 1/20 0.32
SNCA P37840 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113494 0.95
Water SCHEMBL27949772 0.91
SCHEMBL9149406 0.91
SCHEMBL30715500 0.91
Potassium SCHEMBL30715495 0.91
Formaldehyde SCHEMBL27513797 0.87 MAOA (0.33) MAOAMAOBALDH1A1BCHEPOLB
Benzene SCHEMBL28145502 0.87 MAOA (0.37) MAOAMAOBALDH1A1BCHEPOLB
Nitrogen SCHEMBL27904925 0.87 MAOA (0.33) MAOAMAOBALDH1A1BCHEPOLB
Benzoquinone SCHEMBL1298413 0.84 ALDH1A1 (0.61) MAOAMAOBALDH1A1BCHEPOLB
Methyl Alcohol SCHEMBL29048104 0.84 AURKA (0.32) MAOAMAOBALDH1A1BCHEPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776497-A OXIDATIVE POLYMERIZATION OF INDOLINE FOR COSMETICS L'OREAL (FR) 1998-07-07 US claimed