Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630126 | 0.91 | F10 (0.39) | F10CA9CA12CA1CA2 | |
| SCHEMBL8628935 | 0.90 | PTGS2 (0.44) | F10CA9F2PRSS1PRSS2 | |
| SCHEMBL8630001 | 0.90 | PTGS2 (0.44) | F10CA9CA12F2PRSS1 | |
| SCHEMBL8629426 | 0.88 | F10 (0.47) | F10F2 | |
| SCHEMBL7780848 | 0.84 | PTGS2 (0.49) | CA9CA12CA1CA2LMNA | |
| SCHEMBL8631849 | 0.83 | ALOX5AP (0.45) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6746904 | 0.82 | F10 (0.37) | F10CA9CA12F2PRSS1 | |
| SCHEMBL8628010 | 0.81 | PTGS2 (0.53) | F10ALDH1A1 | |
| SCHEMBL8628190 | 0.80 | F10 (0.48) | F10CA9CA12F2PRSS1 | |
| SCHEMBL7780689 | 0.77 | PTGS2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |