Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.38 |
| ▸ | FEN1 | P39748 | 4/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627787 | 0.90 | F10 (0.38) | TRPV1F10CA9F2PRSS1 | |
| SCHEMBL8630126 | 0.89 | F10 (0.39) | ALOX5APFEN1ENPP3F10CA9 | |
| SCHEMBL8630001 | 0.88 | PTGS2 (0.44) | PTGS2PTGS1ENPP3F10CA9 | |
| SCHEMBL8629426 | 0.86 | F10 (0.47) | F10F2 | |
| SCHEMBL8631849 | 0.86 | ALOX5AP (0.45) | ALOX5APFEN1ENPP3F10F2 | |
| SCHEMBL7780383 | 0.83 | PTGS2 (0.50) | PTGS2PTGS1CA9 | |
| SCHEMBL8628010 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1ALOX5APFEN1F10 | |
| SCHEMBL8631026 | 0.82 | CSNK1D (0.53) | PTGS2PTGS1TRPV1ALOX5APFEN1 | |
| SCHEMBL8631051 | 0.79 | PTGS2 (0.48) | PTGS2PTGS1TRPV1ALOX5APFEN1 | |
| SCHEMBL7780848 | 0.77 | PTGS2 (0.49) | PTGS2PTGS1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |