Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GJB2 | P29033 | 1/20 | 0.33 |
| ▸ | GJA1 | P17302 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.30 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907208 | 0.91 | GJB2 (0.37) | MEN1KMT2AGJB2GJA1SSTR1 | |
| SCHEMBL8626852 | 0.88 | MEN1 (0.41) | MEN1KMT2ASLC5A1SLC5A2 | |
| SCHEMBL8628754 | 0.87 | MEN1 (0.34) | MEN1KMT2AGJB2GJA1 | |
| SCHEMBL8627917 | 0.84 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL8624561 | 0.84 | MEN1 (0.33) | MEN1KMT2AGJB2GJA1SSTR4 | |
| SCHEMBL8627578 | 0.83 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL8625319 | 0.81 | GJB2 (0.41) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL8015808 | 0.77 | GJB2 (0.36) | MEN1KMT2AGJB2GJA1SLC5A1 | |
| SCHEMBL21126463 | 0.77 | TACR2 (0.37) | MEN1KMT2A | |
| SCHEMBL18269780 | 0.77 | TACR2 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747463-A | SELECTIN ANTAGONISTS; ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-05 | — | — | US | disclosed |