Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GJB2 | P29033 | 1/20 | 0.30 |
| ▸ | GJA1 | P17302 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907208 | 0.87 | GJB2 (0.37) | MEN1KMT2AGJB2GJA1 | |
| SCHEMBL8627802 | 0.87 | MEN1 (0.40) | MEN1KMT2AGJB2GJA1 | |
| SCHEMBL8625721 | 0.82 | GJB2 (0.37) | GJB2GJA1 | |
| SCHEMBL8626852 | 0.81 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL8627917 | 0.80 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL8624561 | 0.80 | MEN1 (0.33) | MEN1KMT2AGJB2GJA1 | |
| SCHEMBL8627578 | 0.79 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL8015808 | 0.74 | GJB2 (0.36) | MEN1KMT2AGJB2GJA1 | |
| SCHEMBL8626588 | 0.74 | CA2 (0.33) | — | |
| SCHEMBL8628196 | 0.72 | GJB2 (0.43) | GJB2GJA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747463-A | SELECTIN ANTAGONISTS; ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-05 | — | — | US | disclosed |