Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624758 | 0.83 | ALDH1A1 (0.50) | PTPN7KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL8628377 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL8604326 | 0.74 | PTPN7 (0.53) | PTPN7KMT2AMEN1PPARGRAPGEF3 | |
| SCHEMBL29367022 | 0.72 | PTPN7 (1.00) | PTPN7KMT2AMEN1PPARGCASP3 | |
| SCHEMBL25640 | 0.72 | PTPN7 (1.00) | PTPN7KMT2AMEN1PPARGCASP3 | |
| SCHEMBL15201762 | 0.71 | PTPN7 (0.96) | PTPN7KMT2AMEN1PPARGCASP3 | |
| SCHEMBL15201765 | 0.71 | PTPN7 (0.96) | PTPN7KMT2AMEN1PPARGCASP3 | |
| SCHEMBL10902015 | 0.71 | PTPN7 (0.89) | PTPN7KMT2AMEN1PPARGCASP3 | |
| SCHEMBL4076964 | 0.69 | PTPN7 (0.85) | PTPN7KMT2AMEN1PPARGCA2 | |
| Ethylene Glycol SCHEMBL9493499 | 0.68 | PTPN7 (0.90) | PTPN7KMT2AMEN1PPARGCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |