Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193130 | 0.92 | MAPT (0.48) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8540029 | 0.88 | MAPT (0.48) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8626602 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8629851 | 0.85 | KMT2A (0.60) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8873905 | 0.85 | MAPT (0.41) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8628972 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1KMT2ALMNA | |
| SCHEMBL8626593 | 0.84 | MAPT (0.39) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8631357 | 0.82 | KMT2A (0.43) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8627986 | 0.81 | MRGPRX1 (0.40) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8632963 | 0.81 | KMT2A (0.42) | ALDH1A1KDM4EL3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847126-A | N-azinyl-N'-(het) arylsulphonyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5696257-A | INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| US-5580842-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| US-5476936-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-19 | — | — | US | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |