Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628976 | 0.95 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1CYP1A2CYP3A4 | |
| SCHEMBL5193130 | 0.91 | MAPT (0.48) | ALDH1A1KDM4ECYP1A2MAPTKMT2A | |
| SCHEMBL8626602 | 0.88 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1CYP1A2CYP3A4 | |
| SCHEMBL8873905 | 0.86 | MAPT (0.41) | ALDH1A1KDM4EHPGDNPSR1TSHR | |
| SCHEMBL8634470 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4ETDP1CYP1A2CYP3A4 | |
| SCHEMBL8540029 | 0.85 | MAPT (0.48) | ALDH1A1KDM4ETDP1NPC1NPSR1 | |
| SCHEMBL8627862 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1MAPTKMT2A | |
| SCHEMBL8631751 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1CYP1A2CYP3A4 | |
| SCHEMBL8626593 | 0.81 | MAPT (0.39) | ALDH1A1KDM4EHPGDTSHRMAPT | |
| SCHEMBL8651447 | 0.76 | GPR35 (0.42) | ALDH1A1KDM4ENPC1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847126-A | N-azinyl-N'-(het) arylsulphonyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5580842-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| US-5476936-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-19 | — | — | US | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |