SCHEMBL862799

SCHEMBL862799

Cc1ccc2c(c1)oc(=O)c1cc(C)ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.56
MAPT P10636 5/20 0.56
ALDH1A1 P00352 4/20 0.56
KDM4E B2RXH2 4/20 0.56
POLB P06746 2/20 0.56
NPC1 O15118 1/20 0.56
STAT1 P42224 1/20 0.56
RAB9A P51151 1/20 0.56
CDC25A P30304 1/20 0.54
CDC25C P30307 1/20 0.54
PKM P14618 2/20 0.50
MAPK1 P28482 2/20 0.50
GAA P10253 1/20 0.50
HPGD P15428 1/20 0.50
ALPL P05186 1/20 0.50
ALPI P09923 1/20 0.50
ESR1 P03372 2/20 0.49
ESR2 Q92731 2/20 0.49
LMNA P02545 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13924644 0.92 CDC25A (0.54) PDE2AMAPTALDH1A1KDM4EPOLB
SCHEMBL14389015 0.89 NPSR1 (0.64) PDE2AMAPTALDH1A1KDM4EPOLB
SCHEMBL26768244 0.88 PDE2A (0.77) PDE2AMAPTALDH1A1KDM4EGAA
SCHEMBL26767941 0.88 KDM4E (0.54) PDE2AMAPTALDH1A1KDM4EPOLB
SCHEMBL26766495 0.88 ESR2 (0.50) PDE2AMAPTALDH1A1KDM4EPOLB
SCHEMBL14163793 0.88 ESR2 (0.54) PDE2AMAPTALDH1A1KDM4EPOLB
SCHEMBL15395216 0.88 PDE2A (0.77) PDE2AMAPTALDH1A1KDM4EPOLB
SCHEMBL26766664 0.88 MAOB (0.54) PDE2AMAPTALDH1A1KDM4EPOLB
SCHEMBL26766499 0.88 MAPT (0.49) PDE2AMAPTALDH1A1KDM4EPOLB
SCHEMBL26768142 0.87 NPSR1 (0.53) PDE2AMAPTALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230148184-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. 2023-05-11 US disclosed
US-9209404-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-08 US disclosed
US-9209404-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-08 US disclosed
US-9200156-B2 Polymer blends and their use in organic light emitting devices MERCK PATENT GMBH (DE) 2015-12-01 US disclosed
US-9200156-B2 Polymer blends and their use in organic light emitting devices MERCK PATENT GMBH (DE) 2015-12-01 US disclosed
US-9093656-B2 Quantum dots and hosts MERCK PATENT GMBH (DE) 2015-07-28 US disclosed
US-9093656-B2 Quantum dots and hosts MERCK PATENT GMBH (DE) 2015-07-28 US disclosed
US-20130214249-A1 QUANTUM DOTS AND HOSTS MERCK PATENT GMBH (DE) 2013-08-22 US disclosed
US-20130214249-A1 QUANTUM DOTS AND HOSTS MERCK PATENT GMBH (DE) 2013-08-22 US disclosed
US-20120217448-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-30 US disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20080114151-A1 Polymer Compound And Device Using The Same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2008-05-15 US disclosed
US-20080114151-A1 Polymer Compound And Device Using The Same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2008-05-15 US disclosed
US-20080100199-A1 Polymer Material and Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-05-01 US disclosed
US-20080100199-A1 Polymer Material and Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-05-01 US disclosed
US-20080061673-A1 Solution Composition And Polymer Light-Emitting Device SUMITOMO CHEMICAL CO., LTD. (JP) 2008-03-13 US disclosed
US-20080061673-A1 Solution Composition And Polymer Light-Emitting Device SUMITOMO CHEMICAL CO., LTD. (JP) 2008-03-13 US disclosed
WO-2007085377-A2 ELECTROLUMINESCENT MATERIALS AND THEIR USE MERCK PATENT GMBH (DE) 2007-08-02 WO disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties BRS3, SLC43A1, MRPS23 PDE2A 4505/4885MAPT 4058/4885ALDH1A1 4281/4885
US-20230148184-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING RBM17, SNRPA, SNRPA1 PDE2A 1508/4885MAPT 3414/4885ALDH1A1 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.