Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762413 | 0.87 | MAPK1 (0.45) | MAPK1GAALMNAPOLBALDH1A1 | |
| SCHEMBL8624813 | 0.76 | SMN1; SMN2 (0.48) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8762379 | 0.75 | SMN1; SMN2 (0.41) | MAPK1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL8625002 | 0.75 | ECE1 (0.43) | KMT2AMEN1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8761340 | 0.75 | ECE1 (0.47) | LMNAALDH1A1 | |
| SCHEMBL8762388 | 0.73 | ECE1 (0.62) | — | |
| SCHEMBL8762494 | 0.71 | L3MBTL1 (0.50) | MAPK1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL3231132 | 0.71 | HPGD (0.56) | HPGDMAPK1TSHRGAAKMT2A | |
| SCHEMBL1709292 | 0.69 | HPGD (0.65) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL16963757 | 0.69 | HPGD (0.53) | HPGDTSHRGAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636142-B1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LTD (GB) | 1998-06-17 | — | — | EP | disclosed |