Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635102 | 0.92 | PTGS2 (0.43) | PTGS2PTGS1F10P2RX3 | |
| SCHEMBL8629957 | 0.89 | PTGS2 (0.48) | PTGS2PTGS1F10P2RX3 | |
| SCHEMBL8634283 | 0.88 | F10 (0.42) | PTGS2PTGS1F10P2RX3 | |
| SCHEMBL8633042 | 0.87 | PTGS2 (0.41) | PTGS2PTGS1F10 | |
| SCHEMBL8631636 | 0.87 | F10 (0.46) | PTGS2PTGS1F10 | |
| SCHEMBL8630046 | 0.86 | PTGS2 (0.42) | PTGS2PTGS1F10 | |
| SCHEMBL7780086 | 0.86 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8629728 | 0.86 | PTGS2 (0.44) | PTGS2PTGS1F10 | |
| SCHEMBL8634387 | 0.86 | PTGS2 (0.46) | PTGS2PTGS1F10P2RX3BRD4 | |
| SCHEMBL8635364 | 0.85 | PTGS2 (0.44) | PTGS2PTGS1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |