Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.43 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628051 | 0.92 | PTGS2 (0.41) | PTGS2PTGS1F10P2RX3 | |
| SCHEMBL8633042 | 0.89 | PTGS2 (0.41) | PTGS2PTGS1F10F2 | |
| SCHEMBL8631748 | 0.89 | PTGS2 (0.51) | PTGS2PTGS1F10F2 | |
| SCHEMBL8630948 | 0.88 | PTGS2 (0.46) | PTGS2PTGS1F10F2 | |
| SCHEMBL8631636 | 0.87 | F10 (0.46) | PTGS2PTGS1F10F2 | |
| SCHEMBL8630564 | 0.86 | PTGS2 (0.45) | PTGS2PTGS1F10F2 | |
| SCHEMBL7779597 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8629556 | 0.86 | PTGS2 (0.53) | PTGS2PTGS1F10F2 | |
| SCHEMBL8629546 | 0.86 | PTGS2 (0.49) | PTGS2PTGS1F10F2 | |
| SCHEMBL8631727 | 0.86 | PTGS2 (0.44) | PTGS2PTGS1F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |