Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 13/20 | 0.57 |
| ▸ | NCF1 | P14598 | 5/20 | 0.57 |
| ▸ | NOS2 | P35228 | 2/20 | 0.57 |
| ▸ | NCK1 | P16333 | 1/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703616 | 0.80 | BACE1 (0.52) | PLAUBACE1NCF1NOS2NCK1 | |
| Hydrochloric Acid SCHEMBL5263749 | 0.78 | BACE1 (0.50) | PLAUBACE1NCF1NOS2KDM4E | |
| SCHEMBL4503060 | 0.76 | BACE1 (0.65) | PLAUBACE1NCF1NOS2NCK1 | |
| Hydrochloric Acid SCHEMBL6756850 | 0.76 | NCF1 (0.52) | PLAUBACE1NCF1NOS2NCK1 | |
| Hydrochloric Acid SCHEMBL6763944 | 0.76 | NCF1 (0.52) | PLAUBACE1NCF1NOS2NCK1 | |
| SCHEMBL3412309 | 0.76 | PLAU (1.00) | PLAUBACE1NCF1NOS2NCK1 | |
| SCHEMBL30503638 | 0.76 | PLAU (1.00) | PLAUBACE1NCF1NOS2NCK1 | |
| SCHEMBL4045372 | 0.74 | PLAU (0.43) | PLAUBACE1NCF1NOS2NCK1 | |
| SCHEMBL29374605 | 0.74 | BACE1 (1.00) | PLAUBACE1NCF1NOS2NCK1 | |
| SCHEMBL38775 | 0.74 | BACE1 (1.00) | PLAUBACE1NCF1NOS2NCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614915-B1 | Polymer scale preventive agent | SHINETSU CHEMICAL CO (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5420214-A | Process to prevent scale adhesion using condensation product of a diamino heterocyclic and a quinone | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0614915-A1 | Polymer scale preventive agent | Shin-Etsu Chemical Co., Ltd. (JP) | 1994-09-14 | — | — | EP | disclosed |