SCHEMBL8628352

SCHEMBL8628352

CCCC(CCC)CN[C]=O

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
HDAC9 Q9UKV0 1/20 0.30
HDAC5 Q9UQL6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8693114 0.91 ALDH1A1 (0.41) ALDH1A1CYP3A4TSHR
SCHEMBL5269146 0.89 LMNA (0.39) CA1ALDH1A1CYP3A4TSHR
SCHEMBL3140911 0.82 LMNA (0.45) CA2ALDH1A1CYP3A4TSHR
SCHEMBL271571 0.79
SCHEMBL269152 0.78
SCHEMBL79567 0.78 TSHR (0.59) CA1CA2ALDH1A1CYP3A4TSHR
SCHEMBL5844768 0.76
SCHEMBL8309457 0.76 ALDH1A1 (0.52) CA2ALDH1A1CYP3A4TSHR
SCHEMBL8407739 0.70 TSHR (0.35) CA1CA2ALDH1A1CYP3A4TSHR
SCHEMBL5932399 0.69 ALDH1A1 (0.55) CA12CA1CA2CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0560274-B1 Antiherpes peptide derivatives having a ureido N-terminus BOEHRINGER INGELHEIM CA LTD (CA) 1998-06-24 EP claimed
EP-0560274-A1 Antiherpes peptide derivatives having a ureido N-terminus BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP claimed
US-5830864-A RIBONUCLEOTIDE REDUCTASE INHIBITOR BOEHRINGER INGELHEIM (CANADA), LTD. (CA) 1998-11-03 US disclosed
EP-0560274-B1 Antiherpes peptide derivatives having a ureido N-terminus BOEHRINGER INGELHEIM CA LTD (CA) 1998-06-24 EP disclosed
EP-0560274-A1 Antiherpes peptide derivatives having a ureido N-terminus BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP disclosed