Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628412 | 0.88 | AVPR1A (0.44) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL8632229 | 0.85 | AVPR1A (0.47) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL8717630 | 0.84 | AVPR1A (0.57) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL4681804 | 0.80 | AVPR2 (0.48) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL8716136 | 0.78 | AVPR1A (0.47) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL8717780 | 0.77 | AVPR1A (0.54) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL8712963 | 0.76 | AVPR1A (0.69) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL8714659 | 0.76 | AVPR1A (0.57) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL8718316 | 0.75 | AVPR1A (0.56) | AVPR2AVPR1ACHRM1ABCB11HTR1A | |
| SCHEMBL8712973 | 0.73 | AVPR1A (0.54) | AVPR2AVPR1ACHRM1ABCB11HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |