SCHEMBL86285

SCHEMBL86285

O=C1c2ccccc2SC(Cl)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 5/20 0.41
EDNRA P25101 5/20 0.41
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CDC25B P30305 1/20 0.39
MAPK1 P28482 3/20 0.39
CYP1A2 P05177 1/20 0.39
S100A4 P26447 2/20 0.38
IDO1 P14902 1/20 0.34
DNMT1 P26358 1/20 0.34
DNMT3L Q9UJW3 1/20 0.34
DNMT3A Q9Y6K1 1/20 0.34
MAPT P10636 5/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
CES2 O00748 1/20 0.33
APAF1 O14727 1/20 0.33
TERT O14746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL86293 0.78 EDNRB (0.41) EDNRBEDNRAMEN1KMT2ACDC25B
SCHEMBL85993 0.74 MAPT (0.39) EDNRBEDNRAMEN1KMT2ACDC25B
SCHEMBL11762534 0.74 EDNRB (0.38) EDNRBEDNRAMEN1KMT2ACDC25B
SCHEMBL6904734 0.73 MEN1 (0.52) EDNRBEDNRAMEN1KMT2ACDC25B
SCHEMBL31290856 0.68 MEN1 (0.58) MEN1KMT2ACDC25BMAPK1S100A4
SCHEMBL6903914 0.68 MAPK1 (0.67) EDNRBEDNRAMEN1KMT2ACDC25B
SCHEMBL29006544 0.66 S100A4 (0.50) EDNRBEDNRAMEN1KMT2ACDC25B
SCHEMBL5436457 0.65 EDNRB (0.55) EDNRBEDNRAMEN1KMT2ACDC25B
SCHEMBL6901219 0.65 CDC25B (0.52) EDNRBEDNRAMEN1KMT2ACDC25B
SCHEMBL8087837 0.65 MEN1 (0.52) EDNRBEDNRAMEN1KMT2ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 EDNRB 78/4885EDNRA 138/4885MEN1 4036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.