Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | EDNRB | P24530 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14178919 | 0.86 | TYR (0.44) | CDC25BMEN1KMT2AEDNRBEDNRA | |
| SCHEMBL40599 | 0.84 | GPR3 (0.52) | MEN1KMT2ACYP1A2POLBBCHE | |
| SCHEMBL29641604 | 0.84 | GPR3 (0.52) | MEN1KMT2ACYP1A2POLBBCHE | |
| SCHEMBL12185953 | 0.82 | ELANE (0.46) | CDC25BMEN1KMT2AMAPK1CYP1A2 | |
| SCHEMBL21311997 | 0.79 | ACHE (0.39) | KMT2ATYRKDM4EMAPTMAOA | |
| SCHEMBL6903914 | 0.79 | MAPK1 (0.67) | CDC25BMEN1KMT2AEDNRBEDNRA | |
| SCHEMBL13892730 | 0.79 | TYR (0.54) | CDC25BMEN1KMT2AEDNRBEDNRA | |
| SCHEMBL22879476 | 0.79 | CES1 (0.58) | MEN1KMT2ATYRKDM4EMAOA | |
| SCHEMBL12179513 | 0.79 | PTPRC (0.46) | CDC25BMEN1KMT2AEDNRBEDNRA | |
| Bicarbonate SCHEMBL4820941 | 0.78 | HTR7 (0.50) | MEN1KMT2AEDNRBEDNRACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227560-A | Vinylene or exomethylene groups from active methine compounds | THE DOW CHEMICAL COMPANY (US) | 1993-07-13 | — | — | US | claimed |
| US-20150344407-A1 | FENDILINE DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS, INC. | 2015-12-03 | — | — | US | disclosed |
| US-8974769-B2 | Magnetic nanocomposite with multi-biofunctional groups and method for fabricating the same | CHANG GUNG UNIVERSITY (TW) | 2015-03-10 | — | — | US | disclosed |
| US-8974769-B2 | Magnetic nanocomposite with multi-biofunctional groups and method for fabricating the same | CHANG GUNG UNIVERSITY (TW) | 2015-03-10 | — | — | US | disclosed |
| US-8653204-B2 | Carboxylic polybenzimidazole | CHANG GUNG UNIVERSITY (TW) | 2014-02-18 | — | — | US | disclosed |
| US-8653203-B2 | Method for preparing carboxylic polybenzimidazole | CHANG GUNG UNIVERSITY (TW) | 2014-02-18 | — | — | US | disclosed |
| US-8653203-B2 | Method for preparing carboxylic polybenzimidazole | CHANG GUNG UNIVERSITY (TW) | 2014-02-18 | — | — | US | disclosed |
| US-8653204-B2 | Carboxylic polybenzimidazole | CHANG GUNG UNIVERSITY (TW) | 2014-02-18 | — | — | US | disclosed |
| US-8318830-B2 | Photolatent catalysts based on organometallic compounds | BASF SE (DE) | 2012-11-27 | — | — | US | disclosed |
| US-20120035333-A1 | CARBOXYLIC POLYBENZIMIDAZOLE | CHANG GUNG UNIVERSITY (TW) | 2012-02-09 | — | — | US | disclosed |
| US-20120031774-A1 | ELECTRODE FOR AN ELECTROCHEMICAL DEVICE AND METHOD FOR DETECTING HYDROGEN PEROXIDE USING THE ELECTRODE | CHANG GUNG UNIVERSITY (TW) | 2012-02-09 | — | — | US | disclosed |
| US-20120035333-A1 | CARBOXYLIC POLYBENZIMIDAZOLE | CHANG GUNG UNIVERSITY (TW) | 2012-02-09 | — | — | US | disclosed |
| US-20120031774-A1 | ELECTRODE FOR AN ELECTROCHEMICAL DEVICE AND METHOD FOR DETECTING HYDROGEN PEROXIDE USING THE ELECTRODE | CHANG GUNG UNIVERSITY (TW) | 2012-02-09 | — | — | US | disclosed |
| US-20120035334-A1 | METHOD FOR PREPARING CARBOXYLIC POLYBENZIMIDAZOLE | CHANG GUNG UNIVERSITY (TW) | 2012-02-09 | — | — | US | disclosed |
| US-20120035334-A1 | METHOD FOR PREPARING CARBOXYLIC POLYBENZIMIDAZOLE | CHANG GUNG UNIVERSITY (TW) | 2012-02-09 | — | — | US | disclosed |
| US-20110104077-A1 | Magnetic nanocomposite with multi-biofunctional groups and method for fabricating the same | CHANG GUNG UNIVERSITY (TW) | 2011-05-05 | — | — | US | disclosed |
| US-20110104077-A1 | Magnetic nanocomposite with multi-biofunctional groups and method for fabricating the same | CHANG GUNG UNIVERSITY (TW) | 2011-05-05 | — | — | US | disclosed |
| US-20100234485-A1 | PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS | BASF SE (DE) | 2010-09-16 | — | — | US | disclosed |
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234485-A1 | PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS | PUF60, TST, MPST | CDC25B 2213/4885MEN1 2899/4885KMT2A 103/4885 |
| US-20150344407-A1 | FENDILINE DERIVATIVES AND METHODS OF USE THEREOF | KRAS, RASSF5, RASSF2 | CDC25B 1598/4885MEN1 760/4885KMT2A 3273/4885 |
| US-20110104077-A1 | Magnetic nanocomposite with multi-biofunctional groups and method for fabricating the same | CD47, EPCAM, MB | CDC25B 3938/4885MEN1 132/4885KMT2A 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.