Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 8/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | GLP1R | P43220 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630292 | 0.92 | AVPR2 (0.43) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8631280 | 0.87 | AVPR2 (0.49) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8632029 | 0.87 | AVPR2 (0.48) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL4681035 | 0.85 | AVPR2 (0.63) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8712407 | 0.84 | AVPR2 (0.52) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Hydrochloric Acid SCHEMBL8630729 | 0.80 | AVPR2 (0.48) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8630692 | 0.79 | AVPR2 (0.43) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8712361 | 0.79 | AVPR1A (0.70) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8630759 | 0.79 | AVPR1A (0.47) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8715447 | 0.77 | AVPR1A (0.53) | AVPR2AVPR1AABCB11HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |