Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632029 | 0.92 | AVPR2 (0.48) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL8630729 | 0.92 | AVPR2 (0.48) | AVPR2AVPR1ACYP2C9ABCB11ADRB2 | |
| SCHEMBL8630292 | 0.87 | AVPR2 (0.43) | AVPR2AVPR1ACYP2C9USP2ALDH1A1 | |
| SCHEMBL8628740 | 0.79 | AVPR2 (0.48) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4683086 | 0.79 | AVPR2 (0.46) | AVPR2AVPR1ASMN1; SMN2USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4681785 | 0.78 | AVPR2 (0.51) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL4687939 | 0.78 | AVPR2 (0.60) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL8630759 | 0.78 | AVPR1A (0.47) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL4687153 | 0.77 | AVPR2 (0.48) | AVPR2AVPR1ASMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL8631280 | 0.77 | AVPR2 (0.49) | AVPR2AVPR1AABCB11ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |