Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975759 | 0.81 | CASP1 (0.44) | SMN1; SMN2CASP1MEN1KMT2AALDH1A1 | |
| SCHEMBL10976689 | 0.81 | CASP1 (0.44) | SMN1; SMN2CASP1MEN1KMT2AALDH1A1 | |
| SCHEMBL2791101 | 0.80 | SMN1; SMN2 (0.52) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL8628765 | 0.80 | SMN1; SMN2 (0.52) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL2791099 | 0.80 | SMN1; SMN2 (0.52) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL10976804 | 0.78 | MAPT (0.33) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL28968948 | 0.74 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2 | |
| SCHEMBL3077154 | 0.74 | TSHR (0.33) | MAPTCACNA1BAPBA1TDP1TSHR | |
| SCHEMBL15722123 | 0.74 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2 | |
| SCHEMBL28968951 | 0.74 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047428-A | Side effect reduction | SS PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | claimed |