Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLQ | O75417 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627774 | 1.00 | ALDH1A1 (0.40) | ALDH1A1POLQCYP3A4SMN1; SMN2NPC1 | |
| SCHEMBL8621807 | 0.89 | NPSR1 (0.39) | ALDH1A1CYP3A4SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL8624667 | 0.89 | NPSR1 (0.39) | ALDH1A1CYP3A4SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL8627403 | 0.82 | TACR1 (0.38) | ALDH1A1POLQSMN1; SMN2LMNAKMT2A | |
| SCHEMBL8624620 | 0.82 | TACR1 (0.38) | ALDH1A1POLQSMN1; SMN2LMNAKMT2A | |
| SCHEMBL31453537 | 0.81 | MAPT (0.43) | ALDH1A1POLQCYP3A4SMN1; SMN2NPC1 | |
| SCHEMBL798178 | 0.80 | TSHR (0.49) | ALDH1A1POLQCYP3A4SMN1; SMN2NPC1 | |
| SCHEMBL8624142 | 0.77 | NPSR1 (0.39) | ALDH1A1CYP3A4SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL8622855 | 0.77 | NPSR1 (0.39) | ALDH1A1CYP3A4SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL8628963 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP3A4SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684942-B1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORP (US) | 1998-06-10 | — | — | EP | disclosed |
| EP-0684942-A4 | — | — | 1995-12-27 | — | — | EP | disclosed |
| EP-0684942-A1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5430152-A | Heating aminoarylester in presence of chlorosulfonic acid, oleum | HOECHST CELANESE CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1994019312-A1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORPORATION (US) | 1994-09-01 | — | — | WO | disclosed |