Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34663 | 0.87 | CHRM2 (0.42) | FAAHMGLLHTTPOLBMEN1 | |
| SCHEMBL8632299 | 0.84 | MGLL (0.52) | FAAHMGLLSMN1; SMN2HPGDHTT | |
| SCHEMBL8629340 | 0.84 | MGLL (0.52) | FAAHMGLLSMN1; SMN2HPGDHTT | |
| SCHEMBL1982535 | 0.84 | MGLL (0.52) | FAAHMGLLSMN1; SMN2HPGDHTT | |
| SCHEMBL8626070 | 0.84 | MGLL (0.52) | FAAHMGLLSMN1; SMN2HPGDHTT | |
| SCHEMBL8829438 | 0.84 | MGLL (0.52) | FAAHMGLLSMN1; SMN2HPGDHTT | |
| SCHEMBL8862703 | 0.84 | MGLL (0.52) | FAAHMGLLSMN1; SMN2HPGDHTT | |
| SCHEMBL19233361 | 0.84 | MGLL (0.52) | FAAHMGLLSMN1; SMN2HPGDHTT | |
| SCHEMBL8829446 | 0.82 | FAAH (0.53) | FAAHMGLLSMN1; SMN2HPGDHTT | |
| SCHEMBL888672 | 0.77 | MEN1 (0.50) | FAAHMGLLSMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329994-B1 | Immunogen and its use in preparing antibodies to haemoglobin A1C | BOEHRINGER MANNHEIM GMBH (DE) | 1993-12-29 | — | — | EP | claimed |
| CN-117580593-A | Anthracycline antibody conjugates | 思进公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-116847886-A | Immunostimulatory compounds and conjugates | 思进公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116829551-A | Immunomodulatory antibody drug conjugates | 思进公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-115955980-A | Variable charge joint | 思进公司 | 2023-04-11 | — | — | CN | disclosed |
| US-5849863-A | Cytolytic bradykinin antagonists | UNIVERSITY OF COLORADO (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0848718-A1 | CYTOLYTIC BRADYKININ ANTAGONISTS | CORTECH, INC. (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5635593-A | TWO OR MORE BRADYKININ ANTAGONIST PEPTIDES CHEMICALLY LINKED BY ONE OR MORE SUCCINIMIDO GROUP VIA THIOETHER BOND TO FORM DIMER OR HIGHER OLIGOMER | CORTECH, INC. (US) | 1997-06-03 | — | — | US | disclosed |
| US-5620958-A | DIMERIZED PEPTIDES HAVING A BISSUCCINIMIDO GROUP ATTACHED TO CYSTEINE THIO GROUP; ANALGESICS FOR SEVERE PAIN | CORETECH, INC. (US) | 1997-04-15 | — | — | US | disclosed |
| WO-1997009347-A1 | CYTOLYTIC BRADYKININ ANTAGONISTS | CORTECH, INC. (US) | 1997-03-13 | — | — | WO | disclosed |
| EP-0586613-A4 | BRADYKININ ANTAGONISTS | CORTECH INC (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0586613-A1 | BRADYKININ ANTAGONISTS | CORTECH, INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992017201-A1 | BRADYKININ ANTAGONISTS | CORTECH, INC. (US) | 1992-10-15 | — | — | WO | disclosed |
| EP-0329994-A1 | Immunogen and its use in preparing antibodies to haemoglobin A1C | Roche Diagnostics GmbH (DE) | 1989-08-30 | — | — | EP | disclosed |