Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628686 | 0.87 | KCNH2 (0.40) | ROCK2ROCK1SIRT2SIRT1ALDH1A1 | |
| SCHEMBL8625901 | 0.83 | F10 (0.52) | ROCK2ROCK1SIRT2SIRT1ALDH1A1 | |
| SCHEMBL8622748 | 0.79 | F10 (0.43) | ROCK2ROCK1KCNH2F10FNTA | |
| SCHEMBL8622746 | 0.79 | KCNH2 (0.40) | ROCK2ROCK1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL8624162 | 0.79 | F10 (0.54) | ROCK2ROCK1ALDH1A1KCNH2F10 | |
| SCHEMBL7423237 | 0.73 | FNTA (0.51) | ROCK2ROCK1SIRT2SIRT1ALDH1A1 | |
| SCHEMBL7482530 | 0.72 | SIRT2 (0.48) | ROCK2ROCK1SIRT2SIRT1DPP4 | |
| SCHEMBL12009728 | 0.72 | SIRT2 (0.46) | ROCK2ROCK1SIRT2SIRT1ALDH1A1 | |
| SCHEMBL7419120 | 0.72 | SIRT2 (0.48) | ROCK2ROCK1SIRT2SIRT1DPP4 | |
| SCHEMBL8423834 | 0.71 | F10 (0.41) | SIRT2SIRT1ALDH1A1DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731315-A | Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-03-24 | — | — | US | disclosed |