Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 4/20 | 0.40 |
| ▸ | FNTB | P49356 | 4/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CLPP | Q16740 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629049 | 0.87 | ROCK2 (0.39) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL8625901 | 0.81 | F10 (0.52) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL8624162 | 0.78 | F10 (0.54) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7419120 | 0.71 | SIRT2 (0.48) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7482530 | 0.71 | SIRT2 (0.48) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL12009728 | 0.71 | SIRT2 (0.46) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL2329937 | 0.70 | F10 (0.51) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL31110462 | 0.70 | FNTA (0.42) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL8423834 | 0.70 | F10 (0.41) | ADRA1DSIRT2SIRT1ALDH1A1F10 | |
| Hydrochloric Acid SCHEMBL2327302 | 0.70 | SIRT2 (0.47) | KCNH2FNTAFNTBPGGT1BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731315-A | Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-03-24 | — | — | US | disclosed |