SCHEMBL8629288

SCHEMBL8629288

NC(=O)N(c1ccccc1)c1ccc(NC=O)cc1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
NPSR1 Q6W5P4 2/20 0.35
KDM5A P29375 2/20 0.33
KMT2A Q03164 3/20 0.33
KLK1 P06870 2/20 0.33
KLK5 Q9Y337 2/20 0.33
MEN1 O00255 1/20 0.33
NR3C2 P08235 1/20 0.32
TRPM8 Q7Z2W7 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
PLAU P00749 1/20 0.32
PKM P14618 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
ERCC1 P07992 1/20 0.31
ERCC4 Q92889 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7549706 0.77 CYP3A4 (0.43) ALDH1A1NPSR1KMT2AMEN1ESR1
SCHEMBL27576158 0.76 KDM4E (0.46) ALDH1A1NPSR1KDM5AESR1ESR2
SCHEMBL6823836 0.76 ESR1 (0.40) ALDH1A1NPSR1KMT2AESR1ESR2
SCHEMBL5673212 0.75 EPHX1 (0.38) ALDH1A1NPC1HTTRAB9A
SCHEMBL27498642 0.75 CXCR2 (0.44) ALDH1A1NPSR1KMT2AMEN1PLAU
SCHEMBL9267992 0.74 NPSR1 (0.48) ALDH1A1NPSR1KMT2AMEN1TRPM8
SCHEMBL6825878 0.73 MEN1 (0.50) ALDH1A1KMT2AMEN1PKMNPC1
SCHEMBL27516971 0.72 POLQ (0.40) ALDH1A1NPSR1KMT2AMEN1HTT
SCHEMBL27515597 0.72 NPSR1 (0.42) ALDH1A1NPSR1KMT2AMEN1ESR1
SCHEMBL6903658 0.71 ALDH1A1 (0.55) ALDH1A1NPSR1KMT2AMEN1NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570973-B1 Color photographic materials and methods containing DIR or DIAR couplers and phenolic coupler solvents EASTMAN KODAK CO (US) 1998-11-18 EP claimed
EP-0570974-B1 Color photographic materials and methods containing DIR or DIAR couplers and carbonamide coupler solvents EASTMAN KODAK CO (US) 1998-11-18 EP claimed
US-5521057-A COLOR FILMS EASTMAN KODAK COMPANY (US) 1996-05-28 US claimed
US-5514530-A IMPROVED COLOR DENSITY, COLOR NEGATIVE FILMS EASTMAN KODAK COMPANY (US) 1996-05-07 US claimed
US-5510235-A LOW TEMPERATURE STORAGE STABILITY, RESISTANCE TO REDUCTION IN SEASONED BLEACHES EASTMAN KODAK COMPANY (US) 1996-04-23 US claimed
US-5506094-A Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK COMPANY (US) 1996-04-09 US claimed
US-5451496-A Color photographic materials and methods containing DIR or DIAR couplers and phenolic coupler solvents EASTMAN KODAK COMPANY (US) 1995-09-19 US claimed
US-5378593-A DIR=development inhibitor releasing couplers; DIAR=timed development inhibiting releasing couplers EASTMAN KODAK COMPANY (US) 1995-01-03 US claimed
EP-0570973-A1 Color photographic materials and methods containing DIR or DIAR couplers and phenolic coupler solvents EASTMAN KODAK COMPANY (US) 1993-11-24 EP claimed
EP-0570973-B1 Color photographic materials and methods containing DIR or DIAR couplers and phenolic coupler solvents EASTMAN KODAK CO (US) 1998-11-18 EP disclosed
EP-0570974-B1 Color photographic materials and methods containing DIR or DIAR couplers and carbonamide coupler solvents EASTMAN KODAK CO (US) 1998-11-18 EP disclosed
EP-0655648-B1 Photographic elements comprising 2-phenylcarbomoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK CO (US) 1998-06-10 EP disclosed
EP-0636934-B1 Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK CO (US) 1997-02-19 EP disclosed
EP-0651288-B1 Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK CO (US) 1997-02-19 EP disclosed
EP-0651288-A1 Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK COMPANY (US) 1995-05-03 EP disclosed
EP-0636934-A1 Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK COMPANY (US) 1995-02-01 EP disclosed
EP-0636936-A1 Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK COMPANY (US) 1995-02-01 EP disclosed
US-5378593-A DIR=development inhibitor releasing couplers; DIAR=timed development inhibiting releasing couplers EASTMAN KODAK COMPANY (US) 1995-01-03 US disclosed
EP-0570973-A1 Color photographic materials and methods containing DIR or DIAR couplers and phenolic coupler solvents EASTMAN KODAK COMPANY (US) 1993-11-24 EP disclosed
EP-0570974-A1 Color photographic materials and methods containing DIR or DIAR couplers and carbonamide coupler solvents EASTMAN KODAK COMPANY (US) 1993-11-24 EP disclosed