Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559776 | 0.81 | ALDH1A1 (0.64) | ALDH1A1NPSR1KMT2ANPC1RAB9A | |
| SCHEMBL19778 | 0.78 | NPSR1 (0.70) | ALDH1A1NPSR1KMT2ANPC1RAB9A | |
| SCHEMBL11810925 | 0.76 | LMNA (0.47) | ALDH1A1NPSR1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5094831 | 0.76 | NPSR1 (0.67) | ALDH1A1NPSR1KMT2ANPC1RAB9A | |
| Bromide SCHEMBL31210017 | 0.76 | NPSR1 (0.67) | ALDH1A1NPSR1KMT2ANPC1RAB9A | |
| Diphenylamine SCHEMBL10650342 | 0.75 | NPSR1 (0.54) | ALDH1A1NPSR1KMT2ANPC1RAB9A | |
| Dimethylamine SCHEMBL10653757 | 0.74 | NPSR1 (0.58) | ALDH1A1NPSR1KMT2ANPC1RAB9A | |
| SCHEMBL10133326 | 0.74 | ALDH1A1 (0.54) | ALDH1A1NPSR1KMT2ANPC1RAB9A | |
| SCHEMBL23353504 | 0.73 | ALDH1A1 (1.00) | ALDH1A1NPSR1NPC1RAB9ATDP1 | |
| Formanilide SCHEMBL29177030 | 0.73 | ALDH1A1 (1.00) | ALDH1A1NPSR1NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024691-A4 | SOLUBLE POLYMER BASED MATRIX FOR CHEMICALLY ACTIVE WATER INSOLUBLE COMPONENTS | ISP INVESTMENTS INC (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1024691-A1 | SOLUBLE POLYMER BASED MATRIX FOR CHEMICALLY ACTIVE WATER INSOLUBLE COMPONENTS | ISP INVESTMENTS INC. (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1998033378-A1 | SOLUBLE POLYMER BASED MATRIX FOR CHEMICALLY ACTIVE WATER INSOLUBLE COMPONENTS | ISP INVESTMENTS INC. (US) | 1998-08-06 | — | — | WO | disclosed |