SCHEMBL8629368

SCHEMBL8629368

CC(OC(C)C(Cl)Cl)C(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933536 0.75 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1
SCHEMBL1802994 0.69
SCHEMBL2556849 0.65
SCHEMBL7725 0.65
SCHEMBL28671950 0.64 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL12013822 0.64 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL161500 0.64 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL6384032 0.64
SCHEMBL58438 0.64
SCHEMBL352066 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3313822-A1 METHOD FOR SYNTHESIZING AROMATIC OXIMES Compagnie Générale des Etablissements Michelin (FR) 2018-05-02 EP claimed
EP-3313823-A1 METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION Compagnie Générale des Etablissements Michelin (FR) 2018-05-02 EP claimed
WO-2016207263-A1 METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-12-29 WO claimed
WO-2016207261-A1 METHOD FOR SYNTHESIZING AROMATIC OXIMES COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-12-29 WO claimed
CN-106554258-B The method of glycol dimethyl ether co-production ethylene glycol is directly prepared by glycol monoethyl ether 中国科学院大连化学物理研究所 2019-07-26 CN disclosed
EP-3313822-A1 METHOD FOR SYNTHESIZING AROMATIC OXIMES Compagnie Générale des Etablissements Michelin (FR) 2018-05-02 EP disclosed
EP-3313823-A1 METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION Compagnie Générale des Etablissements Michelin (FR) 2018-05-02 EP disclosed
CN-107922320-A Urea derivative and its purposes 东丽株式会社 2018-04-17 CN disclosed
CN-106554258-A The method that glycol dimethyl ether co-production ethylene glycol is directly prepared by glycol monoethyl ether 中国科学院大连化学物理研究所 2017-04-05 CN disclosed
WO-2016207263-A1 METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-12-29 WO disclosed
WO-2016207261-A1 METHOD FOR SYNTHESIZING AROMATIC OXIMES COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-12-29 WO disclosed
CN-103570703-A Preparation and purifying method of tiagabine hydrochloride ZHAO XUEQING 2014-02-12 CN disclosed
CN-1193314-A Process for producing 2-halomethylphenylacetic acid esters SAGAMI CHEM RES (JP) 1998-09-16 CN disclosed
EP-0710641-B1 Process for the preparation of 1,1-dichloromethyl methyl ether and 1,1-dichloromethyl ethyl ether POUDRES & EXPLOSIFS STE NALE (FR) 1998-07-01 EP disclosed
EP-0666854-B1 NEUROPROTECTIVE 3,4-DIHYDRO-2(1H)-QUINOLONE COMPOUNDS PFIZER (US) 1997-03-26 EP disclosed
EP-0710641-A1 Process for the preparation of 1,1-dichloromethyl methyl ether and 1,1-dichloromethyl ethyl ether SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1996-05-08 EP disclosed
EP-0666854-A1 NEUROPROTECTIVE 3,4-DIHYDRO-2(1H)-QUINOLONE COMPOUNDS. PFIZER (US) 1995-08-16 EP disclosed
WO-1994010166-A1 NEUROPROTECTIVE 3,4-DIHYDRO-2(1H)-QUINOLONE COMPOUNDS PFIZER INC. (US) 1994-05-11 WO disclosed
US-5250517-A Hypotensive and cardiotonic agents; cardiac insufficiency HOFFMANN-LA ROCHE INC. (US) 1993-10-05 US disclosed
US-4044131-A B-ADRENERGIC BLOCKERS, FUNGICIDES, 4-ALKYL OR ALKYNYL, 6-ARYLOXYMETHYL AMERICAN HOME PRODUCTS CORPORATION (US) 1977-08-23 US disclosed