SCHEMBL933536

SCHEMBL933536

CC(Cl)C(C)OC(C)C(C)Cl

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8629368 0.75 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1
SCHEMBL161500 0.73 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL12013822 0.73 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL28671950 0.73 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL19343448 0.72
SCHEMBL9118701 0.72
SCHEMBL18840133 0.70 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL23341277 0.69
SCHEMBL9118695 0.69
SCHEMBL16668929 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108627380-B Method for removing or reducing toxic substance and method for detecting toxic substance 中国人民解放军军事医学科学院毒物药物研究所 2020-10-20 CN claimed
CN-112694650-B Wear-resistant bootleg sole and preparation process thereof 莆田永生鞋业有限公司 2022-12-06 CN disclosed
CN-114477212-A Organic functional group modified SBA molecular sieve and preparation method and application thereof 中国石油化工股份有限公司 2022-05-13 CN disclosed
CN-114477202-A Organic functional group modified MCM molecular sieve and preparation method and application thereof 中国石油化工股份有限公司 2022-05-13 CN disclosed
CN-112694650-A Wear-resistant bootleg sole and preparation process thereof 莆田永生鞋业有限公司 2021-04-23 CN disclosed
CN-108627380-B Method for removing or reducing toxic substance and method for detecting toxic substance 中国人民解放军军事医学科学院毒物药物研究所 2020-10-20 CN disclosed
EP-2451765-B1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES UNDER SPECIFIC CONDITIONS SOLVAY (BE) 2016-12-28 EP disclosed
US-9193656-B2 Process for the manufacture of halogenated precursors of alkenones and of alkenones SOLVAY SA (BE) 2015-11-24 US disclosed
EP-2451763-B1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES IN THE PRESENCE OF A SOLVENT SOLVAY (BE) 2015-03-04 EP disclosed
US-8957254-B2 Process for chemical synthesis from an alkenone made from a halogenated precursor SOLVAY SA (BE) 2015-02-17 US disclosed
WO-2011003856-A1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES UNDER SPECIFIC CONDITIONS SOLVAY SA (BE) 2011-01-13 WO disclosed
WO-2011003854-A1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES IN THE PRESENCE OF A SOLVENT SOLVAY SA (BE) 2011-01-13 WO disclosed
EP-1140896-A1 BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 Takeda Chemical Industries, Ltd. (JP) 2001-10-10 EP disclosed
US-6235771-B1 AIDS THERPAY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-05-22 US disclosed
WO-2000037455-A1 BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-06-29 WO disclosed
EP-0413544-B1 Purine derivatives, process for their preparation, pharmaceutical compositions and intermediates BEECHAM GROUP PLC (GB) 1997-01-02 EP disclosed
US-5252575-A Herpes virus BEECHAM GROUP P.L.C. (GB) 1993-10-12 US disclosed
EP-0413544-A2 Purine derivatives, process for their preparation, pharmaceutical compositions and intermediates Beecham Group p.l.c. (GB) 1991-02-20 EP disclosed
US-4125552-A FROM A HALIDE, AMMONIA, HYDROCARBYLAMINE, HYDROGEN SULFIDE AND SULFUR DOW CORNING CORPORATION (US) 1978-11-14 US disclosed
US-4082790-A ORGANIC HALIDE, HYDROGEN SULFIDE, AMMONIA OR AMINE, POLAR SOLVENT DOW CORNING CORPORATION (US) 1978-04-04 US disclosed