Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770635 | 0.77 | USP2 (0.57) | L3MBTL1ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL3770638 | 0.77 | USP2 (0.57) | L3MBTL1ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL11061326 | 0.77 | TSHR (0.69) | TSHRL3MBTL1ALDH1A1HSD17B10RAB9A | |
| SCHEMBL27799475 | 0.74 | TSHR (0.50) | TSHRL3MBTL1ALDH1A1HSD17B10KMT2A | |
| SCHEMBL28831537 | 0.73 | LTB4R2 (0.41) | TSHRL3MBTL1CYP4F2CYP4A11LMNA | |
| Urethane SCHEMBL28707643 | 0.73 | ALOX15 (0.58) | TSHRALDH1A1HSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL27813400 | 0.72 | TSHR (0.47) | TSHRALDH1A1HSD17B10KMT2APOLB | |
| SCHEMBL29130148 | 0.71 | TSHR (0.41) | TSHRALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL27619760 | 0.70 | TSHR (0.45) | TSHRALDH1A1HSD17B10NPC1KMT2A | |
| SCHEMBL27836929 | 0.69 | ALDH1A1 (0.49) | TSHRALDH1A1NPC1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744487-A | PROTEASE INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-04-28 | — | — | US | disclosed |