SCHEMBL8629433

SCHEMBL8629433

O=C1CCC(=O)N1N(N1C(=O)CCC1=O)N1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL3486649 0.84 FFAR3 (0.35)
SCHEMBL8736481 0.73 ALDH1A1 (0.38)
SCHEMBL28361226 0.69
SCHEMBL4132081 0.67 CA12 (0.39)
SCHEMBL12541244 0.66 TSHR (0.32)
SCHEMBL352075 0.66 CA12 (0.33)
SCHEMBL10952648 0.62
SCHEMBL44131 0.62
SCHEMBL13943202 0.59
SCHEMBL9020270 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115124573-A Novel cytotoxic molecules for use in cell binding molecule-drug conjugates 杭州多禧生物科技有限公司 2022-09-30 CN disclosed
CN-1684972-A Conjugates comprised of polymer and HIV gp41-derived peptides and their use in therapy TRIMERIS INC (US) 2005-10-19 CN disclosed
US-5849863-A Cytolytic bradykinin antagonists UNIVERSITY OF COLORADO (US) 1998-12-15 US disclosed
EP-0848718-A1 CYTOLYTIC BRADYKININ ANTAGONISTS CORTECH, INC. (US) 1998-06-24 EP disclosed
WO-1997009347-A1 CYTOLYTIC BRADYKININ ANTAGONISTS CORTECH, INC. (US) 1997-03-13 WO disclosed