Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27970992 | 0.80 | SLC6A3 (0.41) | SMN1; SMN2APEX1ALDH1A1PTGDR2MEN1 | |
| SCHEMBL10484381 | 0.78 | SLC6A3 (0.41) | SMN1; SMN2APEX1PTGDR2MEN1KMT2A | |
| SCHEMBL27860995 | 0.73 | PTGDR2 (0.36) | SMN1; SMN2APEX1ALDH1A1PTGDR2MEN1 | |
| SCHEMBL18324332 | 0.73 | — | — | |
| SCHEMBL1158268 | 0.69 | PTGDR2 (0.40) | ALDH1A1PTGDR2MEN1KMT2AGAA | |
| SCHEMBL13301451 | 0.68 | MEN1 (0.41) | ALDH1A1PTGDR2MEN1KMT2AGAA | |
| SCHEMBL5545037 | 0.65 | SMN1; SMN2 (0.56) | SMN1; SMN2APEX1ALDH1A1PTGDR2GAA | |
| SCHEMBL10403239 | 0.65 | F2 (0.39) | SMN1; SMN2APEX1ALDH1A1CYP1A2 | |
| SCHEMBL9662773 | 0.65 | F2 (0.39) | SMN1; SMN2APEX1ALDH1A1CYP1A2 | |
| SCHEMBL7500533 | 0.65 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |