SCHEMBL8629756

SCHEMBL8629756

C=CCc1ccc2c(ccc3ccccc32)c1O

nearest known ligand 0.84

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
HPRT1 P00492 1/20 0.47
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721648 0.91 GABRA1 (0.52) GABRA1GABRB2
Water SCHEMBL28257828 0.90 GABRA1 (0.50) GABRA1GABRB2
Oxirane SCHEMBL460393 0.84 KDM4E (0.55) GABRA1GABRB2KMT2A
SCHEMBL5615222 0.84 GABRA1 (0.57) GABRA1GABRB2MEN1KMT2A
SCHEMBL30083974 0.81 HPRT1 (0.52) GABRA1GABRB2HPRT1MEN1KMT2A
SCHEMBL17183152 0.81 HPRT1 (0.52) GABRA1GABRB2HPRT1MEN1KMT2A
SCHEMBL1147979 0.81 HPRT1 (0.52) GABRA1GABRB2HPRT1MEN1KMT2A
SCHEMBL6402900 0.80 HPRT1 (0.47) HPRT1MEN1KMT2A
SCHEMBL11223755 0.79 GABRA1 (0.55) GABRA1GABRB2MEN1KMT2A
SCHEMBL29988109 0.79 GABRA1 (0.55) GABRA1GABRB2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553346-B1 PHOTOGRAPHIC PRODUCTS AND PROCESSES POLAROID CORP (US) 1998-01-28 EP claimed