⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18275146 | 0.96 | LMNA (0.39) | — | |
| SCHEMBL28102523 | 0.96 | — | — | |
| SCHEMBL30581182 | 0.76 | — | — | |
| SCHEMBL30581185 | 0.76 | — | — | |
| SCHEMBL2415 | 0.76 | — | — | |
| SCHEMBL173293 | 0.76 | — | — | |
| SCHEMBL4820393 | 0.76 | — | — | |
| SCHEMBL1925147 | 0.76 | ALDH1A1 (0.50) | — | |
| SCHEMBL1190178 | 0.76 | — | — | |
| SCHEMBL1332099 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916215-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| US-20170100352-A1 | Methods for treating or preventing neuroinflammation or autoimmune diseases | ELFORD HOWARD L (US) | 2017-04-13 | — | — | US | claimed |
| EP-2030615-A2 | Ribonucleotide reductase inhibitors for use in the treatment or prevention of neuroinflammatory or autoimmune diseases | ELFORD, Howard L. (US) | 2009-03-04 | — | — | EP | claimed |
| US-20090047250-A1 | Methods for treating or preventing neuroinflammation or autoimmune diseases | ELFORD HOWARD L | 2009-02-19 | — | — | US | claimed |
| EP-1651643-A4 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM LLC (BM) | 2008-10-08 | — | — | EP | claimed |
| EP-1877398-A1 | QUINAZOLINE DERIVATIVES AS EGF AND/OR ERBB2 TYROSINE KINASE INHIBITORS | AstraZeneca AB (SE) | 2008-01-16 | — | — | EP | claimed |
| US-20070259852-A1 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM LLC | 2007-11-08 | — | — | US | claimed |
| US-7253164-B2 | Bicyclic compounds and compositions as PDF inhibitors | IRM LLC (BM) | 2007-08-07 | — | — | US | claimed |
| WO-2006117523-A1 | QUINAZOLINE DERIVATIVES AS EGF AND/OR ERBB2 TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-11-09 | — | — | WO | claimed |
| EP-1651643-A2 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM, LLC (BM) | 2006-05-03 | — | — | EP | claimed |
| WO-2001030979-A1 | PRIMARY N-HYDROXYLAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-05-03 | — | — | WO | claimed |
| US-6028072-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 2000-02-22 | — | — | US | claimed |
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | claimed |
| US-5646319-A | Synthesis of N-acyl-N-alkylcarboxylates | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-08 | — | — | US | claimed |
| EP-0559677-B1 | HYDROXAMIC ACIDS FOR PREVENTING REPERFUSION INJURY | BRITISH TECH GROUP (GB) | 1996-09-11 | — | — | EP | claimed |
| US-5506266-A | CONTROLS FREE RADICAL INDUCED DAMAGE ARISING FROM MYOCARDIAL INFRACTION OR STROKE, PERTICULARYL HEART DAMAGE | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-04-09 | — | — | US | claimed |
| US-5486534-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-01-23 | — | — | US | claimed |
| US-5447934-A | Anti-allergic thiadiazolo [4,3-a]pyridine derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1995-09-05 | — | — | US | claimed |
| EP-0559677-A1 | HYDROXAMIC ACIDS FOR PREVENTING REPERFUSION INJURY. | BRITISH TECH GROUP (GB) | 1993-09-15 | — | — | EP | claimed |
| WO-1992008453-A1 | HYDROXAMIC ACIDS FOR PREVENTING REPERFUSION INJURY | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-05-29 | — | — | WO | claimed |