Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782882 | 0.81 | DPP4 (0.40) | CA12CA9ALDH1A1HSD17B10CYP1B1 | |
| SCHEMBL28888143 | 0.71 | CA12 (0.46) | CA12CA9ALDH1A1HSD17B10HIF1A | |
| SCHEMBL643216 | 0.71 | KDM1A (0.38) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL28424988 | 0.67 | CA12 (0.45) | CA12CA9ALDH1A1HSD17B10HPGD | |
| SCHEMBL7731885 | 0.66 | PRKDC (0.34) | CA12CA9ALDH1A1HSD17B10CYP1B1 | |
| SCHEMBL8680691 | 0.66 | ALDH1A1 (0.48) | CA12CA9ALDH1A1HSD17B10HIF1A | |
| SCHEMBL9245394 | 0.65 | ALDH1A1 (0.41) | CA12CA9ALDH1A1HSD17B10HIF1A | |
| SCHEMBL28558522 | 0.62 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HIF1ACYP1B1HPGD | |
| SCHEMBL27567037 | 0.62 | ALDH1A1 (0.38) | CA12CA9ALDH1A1HSD17B10HIF1A | |
| SCHEMBL22167530 | 0.62 | CYP1A2 (0.36) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707557-A | Photochromic 3H-naphthopyrans | OPTISCHE WERKE G. RODENSTOCK (DE) | 1998-01-13 | — | — | US | disclosed |